• Antibiotic Use in Term and Near-Term Newborns 

      Mundal, Håkon S.; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Størdal, Ketil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      OBJECTIVES - We aimed to study whether national and local antibiotic stewardship projects have reduced the antibiotic use in newborns and to monitor potential changes in adverse outcomes.<p> <p>METHODS - In a nationwide, population-based study from Norway, we included all hospital live births from 34 weeks' gestation (n = 282 046) during 2015 to 2019. The primary outcome was the proportion of ...
    • Early empirical antibiotics and adverse clinical outcomes in infants born very preterm: A population-based cohort 

      Vatne, Anlaug; Hapnes, Nina; Stensvold, Hans Jørgen; Dalen, Ingvild; Guthe, Hans Jørgen Timm; Støen, Ragnhild; Brigtsen, Anne Karin; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-28)
      Objective The objective of this study was to evaluate the association between empirical antibiotic therapy in the first postnatal week in uninfected infants born very preterm and the risk of adverse outcomes until discharge.<p> <p>Study design Population-based, nationwide registry study in Norway including all live-born infants with a gestational age <32 weeks surviving first postnatal week without ...
    • Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study 

      Reigstad, Hallvard; Hufthammer, Karl Ove; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Markestad, Trond Jacob (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-27)
      <p><b> Objective</b> To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. <p><b> Setting</b> All neonatal intensive care units (NICUs) in Norway during 2012–2018. <p><b> Methods</b> Defined population-based data were prospectively entered into a national registry. We ...
    • Late-onset sepsis in very preterm infants in Norway in 2009-2018: A population-based study 

      Huncikova, Zuzana; Vatne, Anlaug; Stensvold, Hans Jørgen; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Salvesen, Bodil; Øymar, Knut Asbjørn Alexander; Rønnestad, Arild Erland; Klingenberg, Claus Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-02)
      Objective To evaluate epidemiology and outcomes among very preterm infants (<32 weeks’ gestation) with culture-positive and culture-negative late-onset sepsis (LOS).<p> <p>Design Cohort study using a nationwide, population-based registry. <p>Setting 21 neonatal units in Norway. <p>Participants All very preterm infants born 1 January 2009–31 December 2018 and admitted to a neonatal ...
    • Predictors of extubation success: a population-based study of neonates below a gestational age of 26 weeks 

      Ohnstad, Mari Oma; Stensvold, Hans Jørgen; Pripp, Are Hugo; Tvedt, Christine Raaen; Jelsness-Jørgensen, Lars-Petter; Astrup, Henriette; Eriksen, Beate Horsberg; Klingenberg, Claus Andreas; Mreihil, Khalaf; Pedersen, Tanja; Rettedal, Siren; Selberg, Terje Reidar; Solberg, Rønnaug; Støen, Ragnhild; Rønnestad, Arild Erland (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-09)
      Objective The aim of the study was to investigate first extubation attempts among extremely premature (EP) infants and to explore factors that may increase the quality of clinical judgement of extubation readiness. Design and method A population-based study was conducted to explore first extubation attempts for EP infants born before a gestational age (GA) of 26 weeks in Norway between 1 January ...
    • Preterm birth in the Nordic countries—Capacity, management and outcome in neonatal care 

      Norman, Mikael; Padkær Petersen, Jesper; Stensvold, Hans Jørgen; Thorkelsson, Thordur; Helenius, Kjell; Brix Andersson, Charlotte; Ørum Cueto, Heidi; Domellöf, Magnus; Gissler, Mika; Heino, Anna; Håkansson, Stellan; Jonsson, Baldvin; Klingenberg, Claus Andreas; Lehtonen, Liisa; Metsäranta, Marjo; Rønnestad, Arild Erland; Trautner, Simon; Vatne, Anlaug; Støen, Ragnhild; Brække, Kristin; Reigstad, Hallvard (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-13)
      Aim - Organisation of care, perinatal and neonatal management of very preterm infants in the Nordic regions were hypothesised to vary significantly. The aim of this observational study was to test this hypothesis.<p> <p>Methods - Information on preterm infants in the 21 greater healthcare regions of Denmark, Finland, Iceland, Norway and Sweden was gathered from national registers in 2021. Preterm ...
    • Variation in antibiotic consumption in very preterm infants-a 10 year population-based study 

      Huncikova, Zuzana; Stensvold, Hans Jørgen; Øymar, Knut Asbjørn Alexander; Vatne, Anlaug; Lang, Astri Maria; Støen, Ragnhild; Brigtsen, Anne Karin; Moster, Dag; Eriksen, Beate Horsberg; Selberg, Terje Reidar; Rønnestad, Arild Erland; Klingenberg, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-21)
      Objectives: Wide variations in antibiotic use in very preterm infants have been reported across centres despite similar rates of infection. We describe 10 year trends in use of antibiotics and regional variations among very preterm infants in Norway. Patients and Methods: All live-born very preterm infants (<32 weeks gestation) admitted to any neonatal unit in Norway during 2009–18 were included. ...